| Idx |
Title |
Pathway |
Keywords |
Tissue-Cell Type |
Disease |
Cell Level |
Ref |
| 1 |
RBphosphoE2F |
- | Cell cycle | ubiquitous | - | nucleus | 8939849 |
| 2 |
Cytokine_Receptors |
- | Cytokine signaling | - | - | intracellular | 7716810 |
| 3 |
T_cell_receptor |
- | Antigen presentation signaling | T cell | - | intracellular, cell membrane, cytoplasm, nucleus, transcription | 7576059 |
| 4 |
cyclins_&_p27_cell_cycle |
- | Cell cycle | ubiquitous | - | nucleus | 8939849 |
| 5 |
B7_CD40_B-cell_activa |
- | B cell activation | immune | - | nucleus | - |
| 6 |
CD23_engagement |
- | Reactive oxygen | monocyte | - | intracellular | 8579750 |
| 7 |
IL17_hematopoesis |
- | Hematopoesis | immune | - | cytoplasm | - |
| 8 |
MonocytesIFNF_IL4 |
- | Monocyte activation | monocyte | - | - | 8579750 |
| 9 |
CKS-17_cytokines |
- | TH1, TH2 | immune | - | intracellular | 8579753 |
| 10 |
Dysdap |
- | muscle | muscle | - | structural | - |
| 11 |
IL-6_gp130-Jak-STAT |
- | Jak/STAT, IL6 | - | - | cell membrane, cytoplasm | 9716487 |
| 12 |
IL-6_type_cytok-signal-transduct |
- | - | - | - | intracellular, cell membrane, cytoplasm, nucleus, transcription | 9716487 |
| 13 |
MS_progression |
- | multiple sclerosis, macrophage, neuron, brain | immune, neural | - | tissue, cellular | 8616884 |
| 15 |
T-cell_polarization-chemokine_receptors |
- | chemokine | T cell | - | intracellular, cell membrane, cytoplasm | 9864948 |
| 18 |
Cytokine_astocytes |
- | multiple sclerosis | astrocyte | - | na | 9918124 |
| 19 |
Cytokine_microglia |
- | multiple sclerosis | microglia | - | na | 9918124 |
| 20 |
Cytokine_oligodendrocytes |
- | multiple sclerosis | oligodendrocyte | - | na | 9918124 |
| 21 |
Cytokine_neurons |
- | multiple sclerosis | neuron | - | na | 9918124 |
| 22 |
Cytokine-chemokine_CNS |
- | multiple sclerosis | - | - | na | 9918124 |
| 23 |
Nongenomic_1a,25-dihydroxyvitamin_D3 |
- | vitamin D3, calcium | ubiquitous | - | cytoplasm | - |
| 24 |
endocannabinoids |
- | cannabinoid, synase | neuron | - | - | 9881850 |
| 25 |
endocannabinoid_neuromodulatory |
- | cannabinoid, synapse channel, neurotransmission | neuron | - | intracellular,cell membrane, cytoplasm | 9881850 |
| 26 |
cyclin-CDK_complexes |
- | cardiac heart, cell cycle, cyclin | heart myocyte | - | nucleus | 9798515 |
| 27 |
Cardiac_myocyte_hypertrophic_growth |
- | cell cycle, cardiac myocyte, hypertrophy | heart myocyte | - | nucleus | 9798515 |
| 28 |
KLFs_cytoplas_dynein_cargo_nerve_axons |
- | axon, dendrite, endosome, dynein | neuron | - | cytoplasm, endosome | 9438838 |
| 29 |
530-kD_cytoplasmic_dynein_heavy_chain |
- | dynein, ankyrin, spectrin | - | - | structural, cytoplasmic | 9438838 |
| 30 |
Kinesin_superfamily_proteins |
- | kinesin | - | - | - | 9438838 |
| 33 |
GProt-coupled_Rec_T_Cell_med_Inflamm |
- | blood brain barrier, pertussis | neural, immune | - | tissue, intracellular | - |
| 34 |
Chemokines_in_EAE |
- | EAE | neural, immune | - | tissue, intracellular | - |
| 35 |
Chemokines_EAE_Autoreactive_T_Cells |
- | EAE, proinflammatory | T cell | - | tissue, intracellular | - |
| 36 |
Death_of_Key_Intracellular_Targets |
- | apoptosis | - | - | cell membrane, cytoplasm | 9620844 |
| 37 |
Akt-PKB_Effector_of_P13K_in_Vivo |
- | - | - | - | cell membrane, cytoplasm | 9038334 |
| 38 |
Cell_cycle_arrest_and_apoptosis_ceramide |
- | apoptosis | - | - | - | 8943189 |
| 39 |
Deg_of_Chromosomal_DNA |
- | apoptosis death | - | - | cell membrane, cytoplasm | 9039262 |
| 40 |
Deg_of_Chrom_DNA_TNF-ind_apoptosis |
- | apoptosis | - | - | cell membrane, cytoplasm | 9039262 |
| 41 |
E2A-HLF_action_in_pro-B_lympocytes |
- | B lymphocytes | - | - | - | 9353180 |
| 42 |
Targets_of_Phosphoinositide_3-Kinases |
- | apoptosis | - | - | - | 9038334 |
| 43 |
Activator-promoter_complex |
- | promotor transcription | - | - | transcription | 9922398 |
| 44 |
Sig_Trans_TNFR1-DR3-DR4_DR5 |
- | signal transduction apoptosis | - | - | cell membrane | 9430227 |
| 45 |
Caspase_activation |
- | apoptosis | - | - | cell membrane, cytoplasm | 10358774 |
| 46 |
P13K_PTEN |
- | tumor suppression | - | - | - | 10200246 |
| 47 |
p13K_and_AKT_suppression_by_PTEN |
- | tumor suppression | - | - | cell membrane | 10200246 |
| 48 |
mice_minus_JAKs_and_STATs |
- | - | - | - | - | 9709499 |
| 49 |
Dystrophin_Glycoprotein_Complex |
- | dystrophin, sarcoglycan | - | - | cell membrane, structural | - |
| 50 |
Hypothesis_of_bronchial_asthma |
- | asthma, mast cell, basophil, eosinophil | basophil, mast | - | intracelular, cell membrane | 9465481 |
| 51 |
CD40_and_EBV |
- | signal transduction | - | - | cell membrane | 9818543 |
| 52 |
B-cell_development_bone_marrow |
- | B cell, bone marrow | B cell | - | intracellular | 9785673 |
| 53 |
Early-response_Tr_Fac_mast_cells |
- | mast cells | mast cell | - | cytoplasm, nucleus, transcription | 9785666 |
| 54 |
T-cell_anergy |
- | T cell anergy | T cell | - | cell membrane, cytoplasm | 9785671 |
| 55 |
Allergen_recognition_by_Th2_or_Th0_cell |
- | asthma, allergy, allergen | - | - | cell membrane | 9666606 |
| 56 |
Macrophage_regulation_of_CD4+T_cells |
- | macrophage, autoimmune | - | - | intracellular | 9639987 |
| 57 |
Post-Golgi&endo_trans_MHC_class_II |
- | golgi, endocytic transport | - | - | endosome | 9639994 |
| 58 |
(CD40L)_immnosurveillance |
- | immunosurveillance | - | - | intracellular, cell membrane | 9639986 |
| 59 |
L-type_Ca2+_Tat_immune_cells |
- | TAT, HIV | - | - | intracellular | 9864943 |
| 60 |
IL-15_rheumatoid-arthritis_synovitis |
- | arthritis | - | - | intracellular, vessel | 9509762 |
| 61 |
Myc_network |
- | Myc | - | - | transcription, nucleus | 9695840 |
| 62 |
G1-phase_progression_by_Myc |
- | cell cycle | - | - | nucleus | 9695840 |
| 63 |
LAT_couples_T-cell_receptor |
- | signaling | - | - | cell membrane, cytoplasm, transcription | 9695835 |
| 64 |
Clathrin-mediated_endocytosis |
- | endocytosis | - | - | cell membrane | 9704404 |
| 65 |
Integrin_affinity_modulation |
- | integrin | - | - | cell membrane, cytoplasm | 9728397 |
| 66 |
Prot_Interac_w_integrin_domains |
- | integrin | - | - | cell membrane, cytoplasm | 9728397 |
| 67 |
Ikaros_and_signaling_inhibitors |
- | T cell signaling | - | - | cell membrane, cytoplasm, nucleus | 10204489 |
| 68 |
Mitogen_signaling_in_growth_control |
- | growth control, mitogen signaling | - | - | cell membrane, cytoplasm | 9695818 |
| 69 |
Survival_signaling_BH3-Bad |
- | apoptosis signaling | - | - | cell membrane, cytoplasm,mitochondria | 9704409 |
| 70 |
Signal_peptides_(MHC)_class_I_molecules |
- | signal peptides | - | - | cell membrane | 9789330 |
| 71 |
Id_proteins_G0-to-S_cell_cycle |
- | cell cycle | - | - | nucleus | 9695810 |
| 72 |
IAP_interaction_with_cell_death_pathways |
- | apoptosis | - | - | cell membrane, cytoplasm | 9990849 |
| 73 |
Integrins_and_other_cell-surface_receptors |
- | integrin | - | - | - | 9789327 |
| 74 |
CD47-IAP_with_avB3 |
- | integrin | - | - | cell membrane | 9789327 |
| 75 |
Stats_activators_of_Apoptosis |
- | apoptosis | - | - | cell membrane, cytoplasm, nucleus | 9695817 |
| 76 |
Sig_trans_Ca2_Calcineurin_NF-AT |
- | calcium, T cell, signal transduction | cardiac | - | cell membrane, cytoplasm, nucleus, transcription | 10089876 |
| 77 |
IkBa_Kinase_JNK_MEKK1 |
- | JNK | - | - | cytoplasm | 9008162 |
| 78 |
B_Cell_Development |
- | B cell development | B cell, monocyte | - | intracellular | 9989493 |
| 79 |
B_cell_Activation |
- | B cell differentiation | B cell | - | intracellular | 9989493 |
| 80 |
T_cell_Activation |
- | T cell | T cell | - | intracellular | 9989493 |
| 81 |
Structure_of_Caps_and_SMACs |
- | Cytoskeleton, lymphocyte activation | - | - | cell membrane | 9989492 |
| 82 |
TCR_and_Cap_or_SMAC |
- | T cell cytoskeleton | - | - | cell membrane, cytoplasm | 9989492 |
| 83 |
Growth_factors_Survival_factors_Mitogens |
- | - | - | - | cell membrane, cytoplasm | 9988218 |
| 84 |
Ubiquitination_Pathways_Cell_Cycle |
- | ubiquitin | - | - | nucleus | 10338207 |
| 85 |
Nuc_Rec-Coact_Complex |
- | transcription complex | - | - | transcription | 10199396 |
| 86 |
Apoptosis_Nematode&_Vert |
- | apoptosis, death | - | - | - | 9988219 |
| 87 |
Activation_ERK-MAPK_Synaptic_Act |
- | synapse, neuron, synapse | neuron | - | cell membrane, cytoplasm, nucleus | 10402188 |
| 88 |
Alternatively_Activated_APC |
- | APC, dendritic cell, macrophage, monocyte | - | - | intracellular | 10072066 |
| 89 |
CD4_T_Cell_Differentiation |
- | T cell, macrophage, TH1, TH2 | - | - | intracellular | 10204493 |
| 90 |
IB_and-cat-Arm_processing_of_Ci |
- | ubiquitin, proteosome | - | - | cytoplasm | 10072378 |
| 91 |
Trials_and_travels_of_tRNA |
- | tRNA, necleolus | - | - | cytoplasm, nucleus | 9887094 |
| 92 |
Ancient_Host_Defense_Pathways |
- | Cell cycle, Rb | - | - | cell membrane, cytoplasm, nucleus | 9734363 |
| 93 |
Insulin-Secretion-Gene-Transcription |
- | insulin, calcium, glucose, liver | - | - | cell membrane, cytoplasm, nucleus, transcription | 9660977 |
| 94 |
E2F_transcriptional_activity_cell_cycle |
- | cell cycle, Rb | - | - | nucleus | 10331086 |
| 95 |
GLUCOSE_PRODUCTION_LIVER |
- | glucose, liver | - | - | cytoplasm | 10448530 |
| 96 |
Immune_injury_MS-lesions_genetic_environ |
- | multiple sclerosis, myelin, MS, neuron, axon | neuron, oligodendrocyte | - | intracellular, tissue | 10392579 |
| 97 |
Immune_injury_MS-lesions_MS_antigen |
- | multiple sclerosis, myelin, MS, neuron, axon | neuron, oligo | - | intracellular, tissue | 10392579 |
| 98 |
Dietary_Fat_and_Gene_Transcription |
- | insulin, glucose, liver | liver | - | nucleus, transcription | 10448517 |
| 99 |
NF-kB_activation |
- | NFkB signaling | - | - | cell membrane, cytoplasm, nucleus | 10354583 |
| 100 |
MAPK_signaling_cascades |
- | mitogen signaling | - | - | cell membrane, cytoplasm, nucleus | 10322405 |
| 101 |
Gprot_coupled_Rec_MAP_Kinase |
- | signal transduction | - | - | cell membrane, cytoplasm, | 10322405 |
| 102 |
Cholesterol_Stress_Response |
- | cholesterol, stress | - | - | cell membrane, cytoplasm, nucleus | - |
| 103 |
Ca2-calmodulin_PK_cascade |
- | calcium, calmodulin | - | - | cytoplasm, nucleus | 10366852 |
| 104 |
Insulin_signaling |
- | insulin | - | - | cell membrane, cytoplasm | 10227847 |
| 105 |
Signaling_glucose_uptake |
- | insulin, glucose | - | - | cell membrane, cytoplasm | 10227847 |
| 106 |
Glycogen_synthase-synthesis |
- | insulin, glycogen | - | - | cell membrane, cytoplasm | 10227847 |
| 107 |
mRNA_translation-protein_synthesis |
- | insulin | - | - | cell membrane, cytoplasm | 10227847 |
| 108 |
Regulating_glucose_transport |
- | insulin | - | - | cell membrane, cytoplasm | 9890935 |
| 109 |
Chemokine_families |
- | inflammation, hematopoeisis, infection | - | - | - | 10562292 |
| 110 |
CRHandLC-NA |
- | stress, HPA axis, immune, infection, allergy, cancer | brain, CNS, lymphoid | - | intracellular | 10511695 |
| 111 |
Stress_influences_immunity |
- | stress, HPA axis, immune, infection, allergy, cancer | mast cell, NK, T cell, macrophage | - | intracellular | 10511695 |
| 112 |
StressandCRHinfluence |
- | stress, HPA axis, immune, infection, allergy, cancer | brain, immune | - | intracellular | 10511695 |
| 113 |
Th1andTh2cells |
- | cellular immunity, humoral immunity, TH1, TH2, cytokine | lymphoid | - | intracellular | 10511695 |
| 115 |
Activation_Rho_family_GTPases |
- | - | - | - | - | 10872457 |
| 116 |
Targets_of_Rho |
- | - | - | - | - | 10872457 |
| 117 |
Targets_of_Rac_and_Cdc42 |
- | - | - | - | - | 10872457 |
| 118 |
Regulation_of_myosin_light_chain |
- | - | - | - | - | 10872457 |
| 119 |
SchizGeneticModel |
- | schizophrenia, genetic, susceptibility, brain | brain | - | - | 10698816 |
| 120 |
SchizSymptomsGenetic |
- | schizophrenia, genetic, susceptibility, brain | brain | - | - | 10698816 |
| 121 |
OligoDiff |
- | oligodendrocyte, myelin, brain, stem cell | brain | - | cellular | 9880596 |
| 123 |
T_cells_and_intestinal_epithelia |
- | inflammation, gut, intestine, T cell | gut, intestine | - | - | 10689299 |
| 124 |
GH-IGF1_thymopoiesis |
- | thymopoiesis, T cell | - | - | - | 10877541 |
| 125 |
T_Cells_CNS-APCs |
- | brain, inflammation, blood brain barrier, astrocyte, microglia | brain | - | - | 10689302 |
| 126 |
Apoptosis-Bcl-2 |
- | mitochondria, stress, apoptosis | mitochondria | - | mitochondria | 10929706 |
| 127 |
Mito-stress |
- | mitochondria, stress, apoptosis | mitochondria | - | mitochondria | 10929706 |
| 128 |
Oxidative_sig-PS-L |
- | mitochondria, stress, apoptosis | - | - | mitochondria | 10899301 |
| 129 |
Oxidative_sig-PS-R |
- | mitochondria, stress, apoptosis | - | - | mitochondria | 10899301 |
| 130 |
normal_artery |
- | Atherosclerosis | artery | - | tissue | 11001066 |
| 131 |
Lesion_initiation |
- | Atherosclerosis | artery | - | tissue | 11001066 |
| 132 |
Atherosclerosis_Inflammation |
- | Atherosclerosis | artery | - | tissue | 11001066 |
| 133 |
Atherosclerosis-Foam-cell_formation |
- | Atherosclerosis | artery | - | tissue | 11001066 |
| 134 |
Atherosclerosis-Fibrous_plaques |
- | Atherosclerosis | artery | - | tissue | 11001066 |
| 135 |
Atherosclerosis_Lesions_Thrombosis |
- | Atherosclerosis | artery | - | tissue | 11001066 |
| 136 |
CG1 |
- | Apoptosis, phagocytosis | APC, phagocytes | - | cell membrane | 10608085 |
| 137 |
Apoptotic_and_Phagocytotic_cell surfaces |
- | Apoptosis, phagocytosis | APC, phagocytes | - | cell membrane | 10679400 |
| 138 |
Fig1AB_Eukaryotic_transcriptional_control |
- | basal transcription | ubiquitous | - | transcription, nucleus | 11040209 |
| 139 |
Fig1CD_Eukaryotic_transcriptional_control |
- | basal transcription | ubiquitous | - | transcription, nucleus | 11040209 |
| 140 |
Fig2_assembly_model_transcription |
- | basal transcription | ubiquitous | - | transcription, nucleus | 11040209 |
| 141 |
Fig3_pre-assembly_model_initiation |
- | basal transcription | ubiquitous | - | transcription, nucleus | 11040209 |
| 142 |
Fig4AB_signal-mediated_transfer_model |
- | basal transcription | ubiquitous | - | transcription, nucleus | 11040209 |
| 143 |
Fig4CD_signal-mediated_transfer_model |
- | basal transcription | ubiquitous | - | transcription, nucleus | 11040209 |
| 144 |
Allergy-inhibition_by_infection1 |
- | atopy, allergy, asthma, infection | - | atopy, allergy, asthma, infection | tissue | 10379050 |
| 145 |
Exacerbation-allergy-infection2 |
- | atopy, allergy, asthma, infection | - | atopy, allergy, asthma, infection | tissue | 10379050 |
| 146 |
Model-Allergy-infection3 |
- | atopy, allergy, asthma, infection | - | atopy, allergy, asthma, infection | tissue | 10379050 |
| 147 |
histone_acetylation_stabilizing_TFIID_interaction |
- | - | ubiquitous | - | transcription, nucleus | 11395415 |
| 148 |
PCAF_GCN5-TFIID-complexes |
- | - | ubiquitous | - | transcription, nucleus | 11395415 |
| 149 |
transcriptional_coactivator_complexes |
- | - | ubiquitous | - | transcription, nucleus | 11395415 |
| 150 |
caspase_and_NFKB_activation |
- | stress, cell death, inflammation | - | - | intracellular | 11393153 |
| 151 |
pro-apoptotic_actions_of_altered_APP&PS1 |
- | Parkinson, Alzheimer, apoptosis | neuron, brain | Parkinson's, Alzheimer's | synapse | 11253364 |
| 152 |
altered_synaptic_signalling-neurodegenerative_disorders |
- | Parkinson, Alzheimer, apoptosis | neuron, brain | Parkinson's, Alzheimer's | synapse | 11253364 |
| 153 |
nucleotide_excision_repair |
- | DNA repair, DNA damage | ubiquitous | xeroderma pigmentosum, Cockayne | nucleus | - |
| 154 |
Transcription-coupled_nucleotide_excision_repair |
- | DNA repair, DNA damage | ubiquitous | xeroderma pigmentosum, Cockayne | nucleus | - |
| 155 |
MBL2-PrimaryBiliaryCirrhosis |
- | PrimaryBiliaryCirrhosis, mannose,MBL2GAD,MBL2 | - | Primary Biliary Cirrhosis | serum | 11712863 |
| 156 |
NOD2-GAD |
- | Crohn's disease,NOD2,NOD2GAD | - | Crohn's disease, Blau syndrome | transcription | 11385576 |
| 157 |
14-3-3_Cell_Cycle |
- | 14-3-3, cell cycle,YHWAH | ubiquitous | - | nucleus | 11598960 |
| 158 |
14-3-3_signal_transduction |
- | 14-3-3, signal transduction,YHWAH | ubiquitous | - | cell membrane,intracellular | 11598960 |
| 159 |
14-3-3_Apoptosis |
- | 14-3-3, apoptosis,YHWAH | ubiquitous | - | intracellular | 11598960 |
| 160 |
abT-cell_development |
- | - | - | - | cell membrane | 11114425 |
| 161 |
Subunits_pre-TCR_and_TCR |
- | TCR, CD3 | T Cell | - | cell membrane | 11114425 |
| 162 |
signal_specification_ pre-TCR |
- | TCR, CD4, CD8 | T Cell | - | cell membrane | 11114425 |
| 163 |
cytokine_receptor_signaling_CD45 |
- | - | - | - | cell membrane | 11323691 |
| 164 |
CCKAR_promoter |
- | CCKA, schizophrenia | - | schizophrenia | promoter | 11549403 |
| 165 |
Caloric_restriction |
- | caloric restriction, glucose, liver, gluconeogenesis | liver | - | intracellular | 10444432 |
| 166 |
MHC_Class_I_Inhibitory_Receptors |
- | MHC | ubiquitous, lymphoid | autoimmune | cell membrane | 11567627 |
| 167 |
MHC_Class_I_related_and_activating_receptors |
- | MHC | ubiquitous, lymphoid | autoimmune | cell membrane | 11567627 |
| 168 |
Wnt_signaling_pathway |
- | Wnt, cadherin, B-catenin | - | - | cell membrane, intracellular | 11532397 |
| 169 |
LPS_stimulation_of_monocytes |
- | septic shock, LPS, endotoxin | monocytes | septic shock | cell membrane, intracellular, transcription | 11257452 |
| 170 |
Toll_proteins |
- | septic shock, LPS, endotoxin | monocytes | septic shock | cell membrane | 11257452 |
| 171 |
human_proximal_CD14_promoter |
- | septic shock, malaria, atopy | monocyte | atopy, septic shock, malaria | promoter | 11698458 |
| 172 |
PRODH2locus |
- | schizophrenia, PRODH2 | - | schizophrenia | - | 11891283 |
| 173 |
calcineurin_signaling_cardiac_myocyte |
- | heart | cardiac myocytes | heart failure, hypertrophic heart disease,cardiomyopathy | intracellular, nucleus | 11922891 |
| 174 |
B-Pix-E20 |
- | brain, development,GTPase | brain | - | tissue | 10860822 |
| 175 |
B-Pix-E18 |
- | brain, development,GTPase | brain | - | tissue | 10860822 |
| 176 |
B-Pix-P0 |
- | brain, development,GTPase | brain | - | tissue | 10860822 |
| 177 |
B-Pix-P7 |
- | brain, development,GTPase | brain | - | tissue | 10860822 |
| 178 |
B-Pix-P12 |
- | brain, development,GTPase | brain | - | tissue | 10860822 |
| 179 |
B-Pix-P18 |
- | brain, development,GTPase | brain | - | tissue | 10860822 |
| 180 |
B-Pix-Adult |
- | brain, development,GTPase | brain | - | tissue | 10860822 |
| 181 |
GPCR_induced_signaling |
- | GPCR, G-Protein, HIV, chemokine | - | HIV | intracellular | 11325604
11325604
11325604 |
| 182 |
Homocysteine_formation |
- | Homocysteine | ubiquitous | Renal failure, Neural tube defects,Hyperhomocysteinemia, Cancer | plasma | 11282420 |
| 183 |
MTHFR_C677T_polymorphism |
- | Homocysteine | ubiquitous | Renal failure, Neural tube defects,Hyperhomocysteinemia, Cancer | plasma | 11282420 |
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